California Phlebotomy Certification Practice Exam

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When educating a patient about a 24-hour urine collection, what instruction should the technician provide?

Start collecting at the first void of the day
Start collecting at the second void of the day
Collect all urine for 48 hours
Refrigerate urine samples during collection

The correct answer is: Start collecting at the second void of the day

The appropriate instruction for a 24-hour urine collection is to start collecting urine at the first void of the day. This practice ensures that the collection period begins at a defined and consistent point in time, which is crucial for the accuracy of test results. The first void marks the start of the 24-hour period, providing a clear delineation of the sample collection timeframe. Starting at the first void helps to include all urine produced during the following 24 hours, offering a comprehensive assessment of the patient's renal function, hormone levels, or any other elements being measured. Proper timing enhances the reliability of the test outcomes, which can be significant for diagnosing conditions or evaluating health status. While the other options may seem relevant, they do not align with the standard protocol required for a 24-hour collection, which specifically emphasizes starting from the first urine void to capture a complete representation of urinary output.